A chronological log of the studies, papers, and clinical analyses we've factored into the Muscle Guard Research Hub. Reverse-chronological order. Updated monthly. If a new paper changes what we publish, the change appears here first.
2026-06-04 — Initial library compilation
First version of the Research Hub published, drawing on 47 peer-reviewed studies across the STEP, SURMOUNT, and SUSTAIN trial families, body-composition substudies, and the broader protein and resistance-training literature.
What changed: Library established. Cornerstone, protein, resistance training, comparison, side-effects timeline, compounded sema, Rybelsus, body recomp, muscle drain, maintenance, the Muscle Guard Score, SA market, doctor visit prep, privacy — 14 articles live.
2026-05-21 — Heymsfield 2024 incorporated
Heymsfield et al. (2024) lean-mass-as-share-of-total-loss meta-analysis was the source we needed for the 25-40% claim with a citation. Prior to this paper, the literature reported the figure but not in a consolidated form.
What changed: Cornerstone article and Evidence PDF cite Heymsfield as [3]. The 25-40% range is now backed by a published, peer-reviewed source rather than synthesised across multiple smaller studies.
2026-04-15 — SURMOUNT-2 data incorporated
SURMOUNT-2 (Garvey et al., 2023) provides tirzepatide weight-loss data in people with type 2 diabetes. We incorporated the body-composition substudy findings into the comparison article.
What changed: Mounjaro vs Ozempic vs Wegovy comparison updated. Tirzepatide efficacy ranges adjusted slightly upward (16-22%, was 14-20%).
What's pending
- SURMOUNT-MAINTAIN follow-up data — expected H2 2026 — will inform the maintenance article.
- EMA decision on oral semaglutide higher-dose formulation — will trigger an update to the Rybelsus article.
- Independent compounded preparation quality analysis (in progress, expected Q4 2026).
Methodology note
We update the library when one of three things happens: a new peer-reviewed study materially changes a claim we make; a regulatory decision changes the landscape; or a published correction makes a prior cited source unreliable. We don't update based on industry reports or marketing materials.
Found a paper we should be reading?
Email research@muscleguardglp.com. We read every suggestion.
Frequently asked questions
How often is this log updated?
Monthly, typically the first week of the month. Material new findings are added immediately and noted in the changelog.
Do you ever remove content?
Rarely. If a cited source is retracted or materially corrected, we update the citing article and note the change here.
Why do you cite some non-peer-reviewed sources?
Industry reports and regulatory body publications are used for market and access claims (drug prices, registration status). These are labelled inline as non-peer-reviewed and dated.
Can I see the full bibliography?
Yes — the 12-page Evidence PDF includes the full citation list, downloadable at /evidence.pdf.
Citations
- [1] Muscle Guard research team (2026). Editorial standards and review process. Internal methodology document, available on request
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