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The protein target on a GLP-1: 1.2 to 1.6 g per kg per day

How much protein you actually need on Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus, or Saxenda to preserve lean muscle. With per-meal targets, serving sizes, and satiety hacks for shot days.

By the Muscle Guard research team · Published 2026-05-19 · Last updated 2026-06-10

The evidence-based protein target on a GLP-1 is 1.2 to 1.6 grams per kilogram of body weight per day, spread across three or four meals of 25 to 40 g each.[¹] At this intake, muscle protein synthesis runs at maintenance or growth, and lean mass loss drops from the 25–40 percent untreated range to under 10 percent.[²] This page covers the daily target, the per-meal target, serving sizes, and what to do when nothing sounds appetising.

Why protein matters more on a GLP-1

Protein does two things on a GLP-1 that nothing else does. First, it triggers muscle protein synthesis — the process that repairs and grows muscle in response to training. Second, it is the most satiating macronutrient gram for gram, which matters less than usual when your appetite is already suppressed, but matters again when appetite starts to creep back during dose plateaus.

Your daily target: 1.2 to 1.6 g/kg/day

For adults on a GLP-1, the evidence-based protein target is 1.2 to 1.6 grams per kilogram of body weight per day. Use the lower end if you are largely sedentary and the upper end if you are resistance-training.

Body weightLower (sedentary)Upper (training)
60 kg72 g96 g
75 kg90 g120 g
90 kg108 g144 g
105 kg126 g168 g

Timing: the per-meal target

Three or four meals containing 25 to 40 g of protein each is the sweet spot. Each of these meals fully stimulates muscle protein synthesis for several hours. Skipping breakfast (a real risk on a GLP-1) cuts your protein opportunities by 25 to 33 percent — start your day with protein even when you are not hungry.

Sources and serving sizes

Satiety hacks when nothing sounds appetising

Many users describe a "food blankness" on a GLP-1 — nothing sounds good, including foods you used to love. Three things help:

Tracking with Muscle Guard

The AI plate scan reads your meal and calculates protein in seconds. The Muscle Guard Score weights daily protein adherence as one of its inputs, so you can see your week-on-week pattern at a glance. The Personal Coach surfaces low-protein days before they become a streak.

Citations

  1. Phillips SM, Chevalier S, Leidy HJ (2016). Protein requirements beyond the RDA. Appl Physiol Nutr Metab. doi.org/10.1139/apnm-2015-0550
  2. Wadden TA et al. (2024). Body Composition Changes with GLP-1 Receptor Agonists. Obesity Reviews.

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Muscle Guard is a self-tracking companion and coach. Not a medical device. Not medical advice. Always consult your healthcare provider for personal decisions.